This post may contain affiliate links. Please read our disclosure policy.

A baked pasta casserole of spaghetti noodles, tender chicken, and mushrooms bathed in a garlicky, creamy sauce, Chicken Tetrazzini has retro flair in the best possible way! This easy, from-scratch recipe gives it a modern twist

the best chicken tetrazzini recipe in casserole dish

Why You’ll Love This Easy Chicken Tetrazzini Recipe

  • Comfort Food Fave. Whether you call it chicken tetrazzini or chicken spaghetti, this is a recipe most of us know, love, and grew up eating. Like Hashbrown Casserole and Chili Mac and Cheese, it’ll give you a warm, fuzzy nostalgic feeling as soon as you take it out of the oven and see that toasty breadcrumb topping.
  • No Cream of Mushroom Soup. No cream of anything soup, in fact! Standing in for the canned soup are cream cheese and plain Greek yogurt (or sour cream), which deliver an even creamier, richer consistency without all the sodium. Even without the canned soup shortcut, this is an easy chicken tetrazzini recipe.
  • ALL the Flavor. Like the Turkey Tetrazzini this recipe is adapted from, this chicken tetrazzini has an amped up flavor profile thanks to the addition of umami Worcestershire sauce, smoked paprika, and sun-dried tomatoes. These ingredients add more depth to the usual creamy-cheesy-carby trifecta, making this the best chicken tetrazzini recipe I’ve ever had. 
  • Great for Using Leftovers. Sometimes I intentionally make extra shredded chicken for chicken tetrazzini, but other times, I’ve got unexpected leftover Instant Pot Chicken or Crock Pot Chicken in the fridge. Any cooked chicken will work here! (Or use it to make Curry Chicken Salad.)
plate of creamy chicken tetrazzini

How to Make Chicken Tetrazzini

The Ingredients

  • Whole Wheat Spaghetti. Using whole wheat noodles sneaks in a little extra nutrition. 
  • Sun-Dried Tomatoes. Drain and pat dry oil-packed sun-dried tomatoes. For dry-packed, cover with hot water until they plump a bit and soften, then drain and pat dry.
  • Yellow Onion and Garlic. These form a savory base of flavor for our chicken tetrazzini.
  • Sliced Mushrooms. I like to use baby bella (also known as cremini) mushrooms because they’re more flavorful than white button.
  • Vinegar. Use red wine, white wine, or champagne vinegar. The acidity enhances the flavor of the casserole.
  • Reduced-Sodium Chicken Broth. While an old-fashioned chicken tetrazzini recipe is laden with sodium, using a lower salt broth lets you control the sodium level by seasoning the dish yourself.
  • Reduced-Fat Cream Cheese. Also known as Neufchatel. This creates a luxuriously creamy sauce.
  • Worcestershire Sauce. Hello, umami flavor bomb! 
  • Smoked Paprika. Why use regular paprika when you can use smoked paprika? This adds the earthy flavor of paprika, with a hit of smokiness.
  • Chicken. Cook and shred yourself, or to make it even easier, rotisserie chicken works too.
  • Frozen Peas and Carrots. Or frozen mixed vegetables, or a single vegetable if you’re serving picky eaters.
  • Cheese. Freshly grated Parmesan cheese for its sharp, pungent flavor, plus shredded Provolone, mozzarella, or Monterey Jack cheese for the melt factor.
  • Whole-Milk Plain Greek Yogurt. One of my favorite tricks for a creamy sauce, as seen in Cauliflower “Mac” and Cheese. Low-fat sour cream would also work. 
  • Panko Breadcrumbs. Essential for that signature golden brown, crispy topping. Homemade breadcrumbs work too, but don’t use the sawdust-like store-bought breadcrumbs—they just won’t cut it.

The Directions

onions cooking in pot for chicken tetrazzini
  1. Get Started. Cook the pasta and sweat the onion until it softens.
sauteed mushrooms in pot for chicken tetrazzini recipe
  1. Cook the Mushrooms. Increase the heat and sauté until they release their liquid.
flour sprinkled over mushrooms in pot
  1. Add the Flour. Stir in the garlic and vinegar, then sprinkle the flour over the mushrooms and stir again. Stream the broth into the pot while stirring, then cook until the sauce reduces by one-third.
mushrooms and sauce in pot for chicken tetrazzini
  1. Make It Creamy. Remove from heat; stir in the cream cheese, Worcestershire, paprika, salt, and pepper.
sauce, chicken, and vegetables in pot for chicken tetrazzini
  1. Add More Ingredients. Fold in the sun-dried tomatoes, chicken, vegetables, and cheeses, then stir in the yogurt. 
chicken tetrazzini in pot
  1. Add the Pasta. Stir in the cooked spaghetti and additional broth, if needed.
chicken tetrazzini in dish before baking
  1. Bake. Transfer to a baking dish and sprinkle panko on top. Bake chicken tetrazzini for 25 minutes, then broil to brown the top, if desired. Rest a few minutes before serving, then ENJOY!

Storage Tips

  • To Store. Refrigerate leftover chicken tetrazzini in an airtight storage container for up to 4 days. 
  • To Reheat. Reheat leftovers in a covered baking dish in the oven at 350 degrees F or in the microwave. 
  • To Freeze. Freeze tetrazzini in an airtight, freezer-safe storage container for up to 3 months. Thaw overnight in the refrigerator before reheating according to the instructions above.

Meal Prep Tip

Cook and shred the chicken up to 1 day in advance. You can also chop the onion and garlic up to 1 day ahead of time. Refrigerate each ingredient in separate airtight containers.

overhead view of chicken tetrazzini with creamy sauce

What to Serve with Chicken Tetrazzini

  • Baking Dish. Choose classic white or go for a pop of color.
  • Dutch Oven. A multitasker that’s made to last a lifetime.
  • Spatula. Heat-resistant so you can stir everything in the pot without worrying about melting plastic.
easy chicken tetrazzini in casserole dish

Recipe Tips and Tricks

  • Grate Your Own Cheese. Freshly grated cheese melts smoother and creamier than the store-bought shreds, which have anti-caking agents added to them. It’s absolutely worth it, whether it’s for this casserole recipe or Cheese Fondue.
  • Cook the Spaghetti to Almost Al Dente. Nope, not al dente! A step below al dente. As with other baked pasta casseroles like Chicken Alfredo Bake, as the chicken tetrazzini bakes, it will absorb some of the liquid from the sauce and cook further. If the pasta noodles are fully cooked, it will end up bloated.
  • Add More Broth If You Need To. Once you add the pasta to the pot, the mixture should be soupy, not thick and creamy. If it’s thick, add more broth. This will keep your chicken tetrazzini from baking up dry.

Chicken Tetrazzini

5 from 10 votes
This easy chicken tetrazzini is the ultimate creamy, cheesy pasta bake recipe. With mushrooms, spaghetti and veggies, it's hearty and delish!

Prep: 15 minutes
Cook: 1 hour 10 minutes
Total: 1 hour 25 minutes

Servings: 8 servings

Ingredients
  

  • 16 ounces whole wheat spaghetti or similar long, thin noodles
  • 1/3 cup sun-dried tomatoes* chopped
  • 3 tablespoons unsalted butter
  • 1 small yellow onion finely chopped
  • 3 cloves garlic minced
  • 16 ounces sliced mushrooms I prefer baby bellas
  • 1 teaspoon red wine, white wine, or champagne vinegar
  • 1/4 cup all-purpose flour
  • 3 to 4 cups reduced sodium chicken broth
  • 4 ounces reduced-fat cream cheese (Neufchatel), cut into pieces
  • 1 tablespoon Worcestershire sauce
  • 1 teaspoon smoked paprika
  • 1 teaspoon kosher salt
  • 1/2 teaspoon black pepper
  • 3 cups cooked, shredded chicken
  • 10 ounces frozen peas and carrots or frozen mixed vegetables
  • 2/3 cup freshly grated Parmesan cheese
  • 2/3 cup shredded Provolone cheese or mozzarella or Monterey Jack cheese
  • 1 cup whole milk plain Greek yogurt
  • 1/2 cup Panko breadcrumbs

Instructions
 

  • Preheat the oven to 350°F. Coat a 9×13 or similarly sized baking dish with nonstick spray and set aside.
  • Break the pasta noodles in half. Cook in salted water according to package instructions until it is just below al dente (it should not be completely crunchy but should still be too chewy to eat; the pasta will cook more in the oven). Drain and set aside.
  • Place the sun-dried tomatoes in a small bowl and cover with hot water. Set aside to rehydrate (if using oil-packed sun-dried tomatoes, you can skip this step; simply drain them and pat off excess oil).
  • In a Dutch oven or similar large, deep pot, heat the butter over medium heat. Add the onion and sauté until softened, about 5 minutes; adjust the heat as needed so that the onion cooks but does not brown.
  • Add the mushrooms then increase to medium-high heat. Sauté until the mushrooms begin to soften and give up their liquid, about 5 minutes.
  • Stir in the garlic and vinegar and let cook 30 seconds.
  • Sprinkle the flour over the top, then stir to coat. Continue cooking and stirring periodically for 2 minutes. No white bits of white flour should remain.
  • Slowly pour in 3 cups of the broth, stirring all the while to avoid any lumps. Bring to a gentle boil and let cook, stirring often to prevent sticking to the bottom of the pot, until the mixture is reduced by about one-third, 6 to 8 minutes.
  • Remove the pan from the heat. Add the diced cream cheese, Worcestershire, smoked paprika, salt, and pepper. Stir until the cream cheese is mostly melted (a few bits may remain, which is fine).
  • Stir in the sun-dried tomatoes, chicken, vegetables, Provolone cheese, and Parmesan cheese, until the cheese is melted. Then stir in the Greek yogurt. Taste and add additional salt and pepper as desired.
  • Add the cooked spaghetti and stir it to combine. If it looks super thick, add more of the remaining 1 cup broth as needed. It should look a little bit soupy, as some of the liquid will cook off in the oven.
  • Transfer the pasta mixture into the prepared baking dish. Sprinkle the Panko over the top. Bake for 25 minutes, or until the tetrazzini is hot and bubbly. If you’d like to brown the topping further, place under the broiler for 1 to 2 minutes, watching carefully so that it does not burn. Remove from the oven and let rest a few minutes before serving.

Notes

  • Adapted from my Turkey Tetrazzini
  • *If using oil-packed sun-dried tomatoes, drain them and pat away excess oil; if using dry-packed, cover them with hot water for a few minutes to soften, then drain and pat dry.
  • TO STORE: Refrigerate leftover chicken tetrazzini in an airtight storage container for up to 4 days. 
  • TO REHEAT: Reheat leftovers in a covered baking dish in the oven at 350 degrees F or in the microwave. 
  • TO FREEZE: Freeze tetrazzini in an airtight, freezer-safe storage container for up to 3 months. Thaw overnight in the refrigerator before reheating according to the instructions above.

Nutrition

Serving: 1(of 8)Calories: 524kcalCarbohydrates: 62gProtein: 35gFat: 17gSaturated Fat: 8gPolyunsaturated Fat: 2gMonounsaturated Fat: 5gTrans Fat: 0.2gCholesterol: 74mgPotassium: 903mgFiber: 3gSugar: 5gVitamin A: 3932IUVitamin C: 7mgCalcium: 279mgIron: 5mg

Join today and start saving your favorite recipes

Create an account to easily save your favorite recipes and access FREE meal plans.

Sign Me Up

Related Recipes

These chicken casseroles are a complete meal in a single dish!

Did you try this recipe?

I want to see!

Follow @wellplated on Instagram, snap a photo, and tag it #wellplated. I love to know what you are making!

You May Also Like

Free Email Series
Sign Up for FREE Weekly Meal Plans
Each includes a grocery list, budget, and 5 healthy dinners, helping you save time, save money, and live better!

Erin Clarke

Hi, I'm Erin Clarke, and I'm fearlessly dedicated to making healthy food that's affordable, easy-to-make, and best of all DELISH. I'm the author and recipe developer here at wellplated.com and of The Well Plated Cookbook. I adore both sweets and veggies, and I am on a mission to save you time and dishes. WELCOME!

Learn more about Erin

Leave a Comment

Did you make this recipe?

Don't forget to leave a review!

Your email address will not be published. Required fields are marked *

Recipe Rating




6 Comments

Leave a comment

  1. One of my go-to meals. It is a little time consuming but it was worth it and I prepare this early in the day so at dinnertime I can just pop it in the oven. I made it with leftover chicken from last night! Was out of panko and used regular bread crumbs instead. I always add extra peas and mushrooms. This was really good. Thank you!5 stars

  2. My husband thought this was amazing and thinks it is one of the best dinners I have ever made. The only thing I did differently from the recipe is I left out the mushrooms since he doesn’t like cooked mushrooms. And I used a Costco rotisserie chicken. I think that was awesome.5 stars

  3. Finally! A dish that the whole family loved. Usually when I make something new, there’s always one person that doesn’t like it, but everyone loves this. It’s not a quick dish to make, but the effort is worth it.5 stars